PGD/PGS (Preimplantation Genetic Diagnosis and Screening)

PGD and PGS are types of genetic testing that are available to perform on a biopsied sample of an embryo created through IVF. The PGS test can determine if an embryo has the correct number of chromosomes and the gender. The PGD test can determine if an embryo is affected or a carrier of a specific disease that has been discovered in either of the parents DNA.

Reasons to consider PGD/PGS?

  • Advanced Age
  • History of Abnormal Pregnancy
  • Carrier of Genetic Disease
  • Recurrent Pregnancy Loss
  • Family Balancing by Gender Selection
  • Chromosomal Translocation discovered in Partner’s Genetic Screening
  • Specific X-Linked Disorders

A woman undergoes a retrieval procedure for her eggs to be fertilized by an embryologist via IVF. On the 5th and 6th days after retrieval, the viable embryos will grow to a blastocyst stage. It is at this stage that the biopsy takes place, in house, removing 4-6 cells from the trophectoderm (which becomes the placenta). The embryos are cryopreserved after the biopsy. The biopsied samples are then shipped to an outsourced company that performs the specific requested test and reports the results directly to DVIF&G. Once the results are reported, The ideal embryo will be chosen for a Frozen Embryo Transfer (FET).

The following links will direct you to well known companies that perform the testing on the samples. There, you can read more detailed information about this option.

www.natera.com/spectrum
www.rgipgd.com